Landela eyodwa Ukudla kwendabuko yaseMedithera Kungaba okungaphezu nje kwesincomo sempilo yenhliziyo noma ukulawula isisindo. Ucwaningo olusha lwesayensi lusikisela ukuthi le ndlela yokudla ingaxhunyaniswa ne- Ukuguga kobuchopho okunempiloukusiza ekunciphiseni ukwehla kwenkumbulo kanye namanye amakhono engqondo kubantu abadala.
Ucwaningo, olwakhiwe yithimba elivela ku- I-Rovira i Virgili University (URV), the I-Pere Virgili Health Research Institute (IISPV) futhi i I-CIBERobn, igxile kubantu baseSpain nge ukukhuluphala ngokweqile noma ukukhuluphala ngokweqile kanye nesifo se-metabolicImiphumela iphakamisa ukuthi labo abadla ukudla kwaseMedithera njalo babonisa ukuthi i-microbiota yamathumbu engcono kakhulu kanye nokwehla kancane kokuqonda eminyakeni edlule.
Ucwaningo lwesikhathi eside nabantu abadala abangu-746
Ucwaningo lushicilelwe kumagazini i-BMC Medicine., kusekelwe kudatha evela ku- 746 abantu abadala ngengozi ephezulu ye-cardiometabolic, kwalandelwa cishe iminyaka eyisithupha. Bonke babeyingxenye yocwaningo olukhulu lwezikhungo eziningi eSpain, oluxhunywe neqembu I-PREDIMED Plus, igxile ebuhlotsheni obuphakathi kokudla nempilo.
Kuyo yonke inqubo yokuqapha, ithimba lesayensi lihlole izindawo ezintathu eziyinhloko: izinga lokunamathela ekudleni kwaseMedithera, lo ukwakheka kwe-gut microbiota futhi i ukuvela komsebenzi wokuqonda Kwababambiqhaza. Ukuze kwenziwe lokhu, kwahlanganiswa imibuzo yokudla, ukuhlaziywa kwamasampula endle kanye nokuhlolwa okujwayelekile kwenkumbulo, ukunaka, ulimi kanye namanye amakhono obuhlakani.
Abacwaningi bathole ukuthi abantu abalandela kakhulu le ndlela yokudla, babonakala nge- ukusetshenziswa kakhulu kwezithelo, imifino kanye nemifinoLabo abadla okusanhlamvu okuphelele, uwoyela womnqumo, amantongomane, nenhlanzi babonise ukuthi i-microbiota yamathumbu icebile ngamagciwane ahlobene nempilo. Ngesikhathi esifanayo, ukusebenza kwabo kwengqondo kwahlala kuzinzile uma kuqhathaniswa nalabo abagwema le ndlela yokudla.
Ngokusho kwababhali, iqiniso lokuthi lolu cwaningo abazoba khona kanye nabaneminyaka eminingi Lokhu kunikeza amandla okuxhumana okubonwe. Nakuba kungasho ngokusobala ukuthi ukudla kwaseMedithera kuyimbangela eqondile yokuvikelwa kwengqondo, kuyawuqinisa umbono wokuthi le ndlela yokudla idlala indima ebalulekile empilweni yobuchopho ngesikhathi sokuguga.
Iyiphi indima edlalwa yi-gut microbiota?
Eminyakeni yamuva nje, izifundo eziningi zihlanganise umqondo wokuthi "i-axis yobuchopho nomgudu wamathumbu"Okusho ukuthi, uhlelo lokuxhumana olunezindlela ezimbili phakathi kohlelo lokugaya ukudla kanye nohlelo lwezinzwa oluphakathi. Amagciwane amathumbu akhiqiza izinto ezinganqamula izithiyo zomzimba, zilawule ukuvuvukala, futhi ekugcineni, thinta ukusebenza kobuchopho.
Ngaphakathi kwalesi simo, umsebenzi omusha we-URV, i-IISPV kanye ne-CIBERobn usekela umbono wokuthi I-microbiota iyisici esibalulekile ngezinzuzo zokuqonda ezihlobene nokudla kwaseMedithera. Umbhali wokuqala wocwaningo, umcwaningi wangaphambi kobudokotela Jiaqi NiKugqamisa ukuthi amanye amabhaktheriya amathumbu, avame kakhulu kulabo abalandela lolu hlobo lokudla ngokuqinile, angaba nomthelela wokuvikela ekuwohlokeni kwamakhono engqondo.
Le ndlela isiza ukuchaza ukuthi kungani kungekona nje kuphela ukuthi yini oyidlayo ebalulekile, kodwa futhi indlela i-ecosystem yamathumbu esabela ngayoAbantu abanezindlela zokudla ezifanayo bangase babonise amaphrofayili ahlukene e-microbiota, okuholela ekuguqukeni kwengqondo okungcono noma okubi kakhulu ngokuguga.
"Unyawo lwe-microbial" njenge-biomarker engaba khona
Esinye sezici ezintsha kakhulu kulolu cwaningo ukuhlonza "unyawo oluthile lwe-microbial" kuhlobene nokudla kwaseMedithera. Lo mqondo ubhekisela kusethi yezimpawu zamagciwane amathumbu, kanye nobuningi bawo, okuvame ukubonwa kulabo abalandela eduze le ndlela yokudla.
Lesi siginesha se-microbial siphakanyiswa njenge- i-biomarker entsha Okungenzeka: ukuba khona kwayo kuhlotshaniswa nokwehla kancane kwengqondo eminyakeni edlule. Ngamanye amazwi, akukhona nje ukulinganisa lokho abantu abakudlayo, kodwa futhi qaphela indlela leyo ndlela yokuphila ebonakala ngayo ku-microbiota yakho futhi, kamuva, ekuthuthukisweni kwempilo yobuchopho babo.
Uprofesa e-URV kanye nomqondisi womsebenzi, UJordi Salas-Salvadó, kugcizelela ukuthi ukuba nalesi "sigxivizo seminwe esibangelwa amagciwane" kuvula umnyango ukuklama ukungenelela kokudla okunempilo noma ngisho namagciwane (isibonelo, ngama-probiotic noma izinguquko ezithile zokudla) okuhloswe ngazo ukukhuthaza ukuguga kwengqondo okunempilo.
Kwabacwaningi boMnyango We-Biochemistry kanye ne-Biotechnology e-URV UNancy Babio noStephanie K. NishiLe miphumela ithola ukubaluleka okukhethekile kumongo we- ukuguga kwabantu kanye nokwanda kwamacala e-dementia eSpain nakwamanye amazwe aseYurophu. Bathi ukuthuthukisa ikhwalithi yokudla kuyindlela elula nefinyelelekayo engaba nomthelela wangempela empilweni yobuchopho.
Imiphumela yezempilo eSpain naseYurophu
ISpain namanye amazwe aseningizimu yeYurophu kubhekwa njengesizinda se- Ukudla kwaseMeditheraKodwa-ke, izifundo eziningana zikhombisile ukuthi le modeli iyayekwa kancane kancane, ikakhulukazi phakathi kwezizukulwane ezisencane. Kubantu abadala asebekhulile abanesisindo esikhulu, ukukhuluphala ngokweqile, kanye nesifo se-metabolic syndrome, ukuqala kabusha noma ukugcina le ndlela kungaba nomthelela omubi empilweni yabo. inzuzo ephindwe kabili: kuthuthukisa impilo ye-cardiometabolic futhi, ngesikhathi esifanayo, kusiza ekulondolozeni ukusebenza kwengqondo.
I-Metabolic syndrome, ebonakala ngokuhlanganiswa kwezinto ezifana umfutho wegazi ophakeme, amafutha amaningi esiswini, amazinga kashukela ashintshile kanye namafuthaKuhlotshaniswa nengozi eyengeziwe yesifo senhliziyo nesifo sikashukela sohlobo 2. Lolu cwaningo olusha lunezela olunye ucezu empikiswaneni ngokusikisela ukuthi lungase luhileleke nase- ukuqala noma ukusheshisa kokwehla kwengqondonokuthi ukudla kwaseMedithera kunganciphisa kancane le ngozi.
Empeleni, imiphumela isekela izincomo esezivamile kakade eziqondisweni zezempilo zomphakathi zaseYurophu: Khulisa ukusetshenziswa kokudla okusha okusekelwe ezitshalweni, beka phambili uwoyela womnqumo omsulwa njengamafutha ayinhloko, khetha inhlanzi kunenyama ebomvu futhi unciphise imikhiqizo ecutshungulwe kakhulu kanye noshukela owengeziweKunokuba kube yisiqondiso esiqinile, kuyindlela yokudla evumelana nezimo zamasiko ezahlukene eYurophu.
Nokho, abalobi bagcizelela isidingo socwaningo olwengeziwe ukuze bachaze ngokunembile yiziphi izingxenye ezithile zokudla kwaseMedithera (isibonelo, izinhlobo ezithile ze-fiber, ama-polyphenols, noma amafutha anempilo) zinomthelela omkhulu ku-microbiota kanye nomsebenzi wokuqonda, nokuthi lokhu okutholakele kungahunyushwa kanjani ku- izinhlelo zokuvimbela ezinkulu.
Njengoba kunikezwe ukwanda kwesikhathi sokuphila kanye nokusabalala okukhulu kwezifo ezifana ne-dementia, lolu hlobo lobufakazi luqinisa umqondo wokuthi ukunakekela ukudla komuntu kusukela ebudaleni obuphakathi nobudala Akugcini nje ngokuthinta inhliziyo noma isisindo, kodwa futhi nekhono lokugcina ukuzimela kanye nekhwalithi yokuphila eminyakeni ezayo.
